Cheapest return flights from Santiago to La Serena in October from $58

AirHint found the following cheapest return flights from Santiago (SCL) to La Serena (LSC) in October 2025 (see full year).

Return flights

09 Oct - 12 Oct JetSmart direct
12 Oct - 26 Oct JetSmart direct
09 Oct - 10 Oct JetSmart direct
09 Oct - 26 Oct JetSmart direct
23 Oct - 26 Oct JetSmart direct
04 Oct - 10 Oct JetSmart direct
23 Oct - 08 Nov JetSmart direct
23 Oct - 02 Nov JetSmart direct
23 Oct - 10 Nov JetSmart direct
12 Oct - 31 Oct JetSmart direct
23 Oct - 31 Oct JetSmart direct
04 Oct - 05 Oct JetSmart direct
24 Oct - 26 Oct JetSmart direct
30 Oct - 02 Nov JetSmart direct
30 Oct - 10 Nov JetSmart direct
24 Oct - 02 Nov JetSmart direct
24 Oct - 10 Nov JetSmart direct
30 Oct - 08 Nov JetSmart direct
24 Oct - 08 Nov JetSmart direct
17 Oct - 02 Nov JetSmart direct

Also check the deals for one-way flights from Santiago to La Serena in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in La Serena

Cheap car rent in La Serena

Feel free to contact us with any feedback or request another flight research.