Cheapest return flights from Santiago to La Serena in October from $51

AirHint found the following cheapest return flights from Santiago (SCL) to La Serena (LSC) in October 2025 (see full year).

Return flights

08 Oct - 12 Oct LATAM Airlines Group direct
11 Oct - 12 Oct LATAM Airlines Group direct
23 Oct - 26 Oct LATAM Airlines Group direct
02 Oct - 05 Oct LATAM Airlines Group direct
18 Oct - 21 Oct LATAM Airlines Group direct
09 Oct - 13 Oct LATAM Airlines Group direct
04 Oct - 05 Oct LATAM Airlines Group direct
02 Oct - 06 Oct LATAM Airlines Group direct
25 Oct - 26 Oct LATAM Airlines Group direct
30 Oct - 02 Nov LATAM Airlines Group direct
06 Oct - 21 Oct LATAM Airlines Group direct
21 Oct - 08 Nov JetSmart direct
21 Oct - 06 Nov JetSmart direct
21 Oct - 10 Nov JetSmart direct
21 Oct - 01 Nov JetSmart direct
25 Oct - 06 Nov Sky Airline direct
23 Oct - 08 Nov JetSmart direct
25 Oct - 01 Nov Sky Airline direct
25 Oct - 14 Nov JetSmart direct
25 Oct - 08 Nov JetSmart direct

Also check the deals for one-way flights from Santiago to La Serena in October.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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