Cheapest return flights from Santiago to La Serena in December from $59

AirHint found the following cheapest return flights from Santiago (SCL) to La Serena (LSC) in December 2025 (see full year).

Return flights

14 Dec - 27 Dec JetSmart direct
14 Dec - 25 Dec JetSmart direct
19 Dec - 27 Dec JetSmart direct
19 Dec - 25 Dec JetSmart direct
23 Dec - 27 Dec JetSmart direct
23 Dec - 25 Dec JetSmart direct
04 Dec - 25 Dec JetSmart direct
27 Dec - 31 Dec Sky Airline direct
11 Dec - 19 Jan LATAM Airlines Group direct
31 Dec - 04 Jan Sky Airline direct
04 Dec - 12 Dec JetSmart direct
04 Dec - 07 Dec Sky Airline direct
26 Dec - 04 Jan JetSmart direct
23 Dec - 12 Jan JetSmart direct
27 Dec - 12 Jan JetSmart direct

Also check the deals for one-way flights from Santiago to La Serena in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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