Cheapest return flights from Santiago to La Serena in December from $64

AirHint found the following cheapest return flights from Santiago (SCL) to La Serena (LSC) in December 2025 (see full year).

Return flights

21 Dec - 26 Dec LATAM Airlines Group direct
21 Dec - 21 Dec LATAM Airlines Group direct
28 Dec - 02 Jan LATAM Airlines Group direct
29 Dec - 02 Jan Sky Airline direct
28 Dec - 31 Dec LATAM Airlines Group direct
22 Dec - 09 Jan Sky Airline direct
25 Dec - 14 Jan JetSmart direct
25 Dec - 06 Jan JetSmart direct
25 Dec - 07 Jan JetSmart direct
25 Dec - 15 Jan JetSmart direct
17 Dec - 19 Dec Sky Airline direct
29 Dec - 08 Jan Sky Airline direct
16 Dec - 21 Dec Sky Airline direct
25 Dec - 27 Dec Sky Airline direct
14 Dec - 20 Dec JetSmart direct
14 Dec - 16 Dec JetSmart direct
14 Dec - 25 Dec JetSmart direct
22 Dec - 23 Dec Sky Airline direct
30 Dec - 13 Jan LATAM Airlines Group direct
26 Dec - 02 Jan LATAM Airlines Group direct

Also check the deals for one-way flights from Santiago to La Serena in December.

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