AirHint found the following cheapest return flights from Santiago (SCL) to Madrid (MAD) in September 2025 (see full year).

Return flights

25 Sep - 30 Sep	Sky Airline
03 Sep - 09 Sep	LATAM Airlines Group
21 Sep - 06 Oct	Avianca
23 Sep - 17 Oct	Avianca
05 Sep - 11 Sep	Sky Airline
26 Sep - 06 Oct	Sky Airline
21 Sep - 05 Oct	Sky Airline
21 Sep - 29 Sep	Sky Airline
30 Sep - 21 Oct	Avianca
26 Sep - 17 Oct	Avianca
06 Sep - 13 Sep	LATAM Airlines Group
19 Sep - 23 Sep	Sky Airline
26 Sep - 27 Oct	Avianca
29 Sep - 06 Oct	Avianca
02 Sep - 11 Sep	Sky Airline
20 Sep - 30 Sep	Sky Airline
21 Sep - 30 Sep	LATAM Airlines Group
08 Sep - 15 Sep	LATAM Airlines Group
23 Sep - 06 Oct	Sky Airline
23 Sep - 05 Oct	Sky Airline

Also check the deals for one-way flights from Santiago to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Madrid in September from $945

Return flights