AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

25 Oct - 09 Nov	JetSmart
28 Oct - 09 Nov	JetSmart
27 Oct - 09 Nov	JetSmart
26 Oct - 09 Nov	JetSmart
20 Oct - 09 Nov	JetSmart
18 Oct - 20 Oct	JetSmart
15 Oct - 20 Oct	JetSmart
28 Oct - 16 Nov	JetSmart
17 Oct - 20 Oct	JetSmart
05 Oct - 08 Oct	LATAM Airlines Group
01 Oct - 06 Oct	LATAM Airlines Group
23 Oct - 27 Oct	LATAM Airlines Group
01 Oct - 13 Oct	LATAM Airlines Group
19 Oct - 09 Nov	JetSmart
08 Oct - 20 Oct	JetSmart
16 Oct - 20 Oct	JetSmart
10 Oct - 14 Oct	LATAM Airlines Group
26 Oct - 11 Nov	LATAM Airlines Group
27 Oct - 16 Nov	JetSmart
27 Oct - 08 Nov	LATAM Airlines Group

Also check the deals for one-way flights from Santiago to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in October from $311

Return flights