AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

29 Dec - 07 Jan	JetSmart	direct
02 Dec - 12 Dec	JetSmart
02 Dec - 07 Dec	JetSmart
29 Dec - 06 Jan	JetSmart	direct
05 Dec - 12 Dec	JetSmart	direct
12 Dec - 13 Dec	JetSmart
04 Dec - 12 Dec	JetSmart
04 Dec - 07 Dec	JetSmart
02 Dec - 13 Dec	JetSmart
02 Dec - 06 Dec	JetSmart
08 Dec - 12 Dec	JetSmart	direct
02 Dec - 11 Dec	JetSmart
22 Dec - 04 Jan	JetSmart	direct
28 Dec - 25 Jan	JetSmart	direct
19 Dec - 11 Jan	JetSmart	direct
19 Dec - 12 Jan	JetSmart
12 Dec - 10 Jan	JetSmart
31 Dec - 11 Jan	JetSmart
25 Dec - 11 Jan	JetSmart
31 Dec - 14 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in December from $306

Return flights