AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

09 Dec - 16 Dec	Copa
08 Dec - 21 Dec	Copa
31 Dec - 18 Jan	JetSmart
08 Dec - 15 Dec	Copa
08 Dec - 11 Dec	Copa
08 Dec - 12 Dec	Copa
08 Dec - 25 Dec	Copa
24 Dec - 25 Dec	JetSmart
27 Dec - 29 Dec	JetSmart
24 Dec - 29 Dec	JetSmart
31 Dec - 11 Jan	JetSmart
28 Dec - 29 Dec	JetSmart
28 Dec - 18 Jan	JetSmart
30 Dec - 18 Jan	JetSmart
27 Dec - 11 Jan	JetSmart
24 Dec - 11 Jan	JetSmart
31 Dec - 13 Jan	JetSmart
28 Dec - 11 Jan	JetSmart
30 Dec - 11 Jan	JetSmart
31 Dec - 04 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in December from $377

Return flights