AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in April 2026 (see full year).

Return flights

24 Apr - 24 Apr	JetSmart	direct
17 Apr - 24 Apr	JetSmart	direct
21 Apr - 24 Apr	JetSmart	direct
17 Apr - 23 Apr	JetSmart
21 Apr - 23 Apr	JetSmart
14 Apr - 24 Apr	JetSmart	direct
07 Apr - 24 Apr	JetSmart	direct
07 Apr - 10 Apr	JetSmart	direct
14 Apr - 23 Apr	JetSmart
07 Apr - 23 Apr	JetSmart
17 Apr - 01 May	JetSmart	direct
21 Apr - 01 May	JetSmart	direct
24 Apr - 01 May	JetSmart	direct
14 Apr - 01 May	JetSmart	direct
24 Apr - 02 May	JetSmart
17 Apr - 02 May	JetSmart
21 Apr - 02 May	JetSmart
24 Apr - 03 May	JetSmart	direct
17 Apr - 03 May	JetSmart	direct
21 Apr - 03 May	JetSmart	direct

Also check the deals for one-way flights from Santiago to Rio Negro in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in April from $285

Return flights