AirHint found the following cheapest return flights from Santiago (SCL) to Mexico City (MEX) in October 2025 (see full year).

Return flights

01 Oct - 07 Oct	Arajet
01 Oct - 16 Oct	Arajet
03 Oct - 19 Oct	Avianca
03 Oct - 20 Oct	LATAM Airlines Group	direct
21 Oct - 28 Oct	Avianca
23 Oct - 27 Oct	Avianca
15 Oct - 25 Oct	Copa
09 Oct - 17 Oct	Copa
01 Oct - 01 Oct	Arajet
01 Oct - 11 Oct	Avianca
02 Oct - 02 Nov	Copa
24 Oct - 30 Nov	Avianca
24 Oct - 04 Nov	Avianca
23 Oct - 04 Nov	Avianca
16 Oct - 06 Nov	Sky Airline
28 Oct - 13 Nov	Avianca
29 Oct - 04 Nov	Sky Airline
29 Oct - 07 Nov	Sky Airline
28 Oct - 05 Nov	LATAM Airlines Group
26 Oct - 13 Nov	Avianca

Also check the deals for one-way flights from Santiago to Mexico City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Mexico City in October from $471

Return flights