AirHint found the following cheapest return flights from Santiago (SCL) to Mexico City (MEX) in October 2025 (see full year).

Return flights

01 Oct - 07 Oct	Arajet
19 Oct - 26 Oct	Avianca
02 Oct - 07 Oct	Avianca
01 Oct - 16 Oct	Arajet
14 Oct - 25 Nov	Avianca
02 Oct - 12 Oct	Avianca
03 Oct - 12 Oct	Avianca
06 Oct - 12 Oct	Avianca
12 Oct - 19 Oct	Avianca
10 Oct - 12 Nov	LATAM Airlines Group	direct
08 Oct - 24 Oct	Avianca
02 Oct - 06 Oct	Avianca
09 Oct - 09 Nov	Avianca
04 Oct - 30 Nov	LATAM Airlines Group	direct
13 Oct - 21 Nov	Arajet
27 Oct - 10 Nov	Aeromexico	direct
28 Oct - 11 Nov	Avianca
27 Oct - 03 Nov	Aeromexico	direct
31 Oct - 16 Nov	Aeromexico	direct
20 Oct - 21 Nov	Arajet

Also check the deals for one-way flights from Santiago to Mexico City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Mexico City in October from $433

Return flights