AirHint found the following cheapest return flights from Santiago (SCL) to Mexico City (MEX) in September 2025 (see full year).

Return flights

24 Sep - 07 Oct	Arajet
24 Sep - 30 Sep	Arajet
23 Sep - 07 Oct	Avianca
23 Sep - 30 Sep	Avianca
26 Sep - 19 Oct	Avianca
24 Sep - 03 Oct	Avianca
29 Sep - 30 Sep	Arajet
26 Sep - 06 Oct	Avianca
22 Sep - 28 Sep	Arajet
26 Sep - 05 Oct	Avianca
25 Sep - 22 Oct	Avianca
26 Sep - 04 Oct	Avianca
26 Sep - 06 Oct	LATAM Airlines Group	direct
23 Sep - 01 Oct	Avianca
18 Sep - 29 Sep	Avianca
14 Sep - 29 Sep	LATAM Airlines Group
18 Sep - 24 Sep	Avianca
24 Sep - 29 Sep	Arajet
11 Sep - 24 Sep	LATAM Airlines Group	direct
08 Sep - 30 Sep	Avianca

Also check the deals for one-way flights from Santiago to Mexico City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Mexico City in September from $472

Return flights