AirHint found the following cheapest return flights from Santiago (SCL) to Panama City (PTY) in June 2025 (see full year).

Return flights

26 Jun - 03 Jul	Avianca
30 Jun - 07 Jul	Avianca
18 Jun - 21 Jun	Avianca
19 Jun - 22 Jun	Avianca
24 Jun - 04 Jul	Avianca
26 Jun - 03 Jul	Copa	direct
19 Jun - 22 Jun	Copa	direct
20 Jun - 29 Jun	Copa	direct
18 Jun - 21 Jun	Copa	direct
19 Jun - 23 Jun	Copa	direct
17 Jun - 28 Jul	Avianca
30 Jun - 07 Jul	Copa	direct
17 Jun - 28 Jul	Copa	direct

Also check the deals for one-way flights from Santiago to Panama City in June.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City

Cheapest return flights from Santiago to Panama City in June from $576

Return flights