Cheapest return flights from Santiago to Prague in October from $153

AirHint found the following cheapest return flights from Santiago (SCQ) to Prague (PRG) in October 2025 (see full year).

Return flights

13 Oct - 17 Oct Vueling Airlines
04 Oct - 10 Oct Vueling Airlines
18 Oct - 21 Oct Ryanair
15 Oct - 19 Oct Vueling Airlines
02 Oct - 08 Oct Ryanair
31 Oct - 05 Nov Vueling Airlines
31 Oct - 06 Nov Vueling Airlines
01 Oct - 07 Oct Vueling Airlines
01 Oct - 11 Oct Vueling Airlines
07 Oct - 11 Oct Vueling Airlines
18 Oct - 06 Nov Vueling Airlines
18 Oct - 05 Nov Vueling Airlines
07 Oct - 07 Oct Vueling Airlines
04 Oct - 07 Oct Vueling Airlines
15 Oct - 05 Nov Vueling Airlines
31 Oct - 18 Nov Vueling Airlines

Also check the deals for one-way flights from Santiago to Prague in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Feel free to contact us with any feedback or request another flight research.