Cheapest return flights from Santiago to Prague in October from $179

Best time to book flights for Santiago (SCQ) to Prague (PRG) flights at AirHint

AirHint found the following cheapest return flights from Santiago (SCQ) to Prague (PRG) in October 2025 (see full year).

Return flights

15 Oct - 22 Oct Vueling Airlines
07 Oct - 10 Oct Ryanair
22 Oct - 06 Nov Vueling Airlines
31 Oct - 06 Nov Vueling Airlines
14 Oct - 22 Oct Vueling Airlines
19 Oct - 06 Nov Vueling Airlines
14 Oct - 15 Oct Vueling Airlines
07 Oct - 22 Oct Vueling Airlines
19 Oct - 22 Oct Vueling Airlines
07 Oct - 15 Oct Vueling Airlines
31 Oct - 17 Nov Vueling Airlines

Also check the deals for one-way flights from Santiago to Prague in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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