Cheapest return flights from Santiago to Prague in December from $170

AirHint found the following cheapest return flights from Santiago (SCQ) to Prague (PRG) in December 2025 (see full year).

Return flights

02 Dec - 06 Dec Vueling Airlines
07 Dec - 10 Dec Vueling Airlines
07 Dec - 11 Dec Vueling Airlines
02 Dec - 05 Dec Vueling Airlines
02 Dec - 12 Dec Vueling Airlines
01 Dec - 06 Dec Iberia
09 Dec - 10 Dec Vueling Airlines
09 Dec - 11 Dec Vueling Airlines
09 Dec - 17 Dec Vueling Airlines
02 Dec - 03 Dec Vueling Airlines
30 Dec - 05 Jan Iberia
27 Dec - 13 Jan Vueling Airlines
25 Dec - 13 Jan Vueling Airlines
30 Dec - 04 Jan Iberia
30 Dec - 03 Jan Iberia
18 Dec - 05 Jan Vueling Airlines
30 Dec - 13 Jan Vueling Airlines
27 Dec - 03 Jan Vueling Airlines
18 Dec - 04 Jan Vueling Airlines
26 Dec - 03 Jan Iberia

Also check the deals for one-way flights from Santiago to Prague in December.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Feel free to contact us with any feedback or request another flight research.