Cheapest return flights from Santiago to Prague in December from $217

AirHint found the following cheapest return flights from Santiago (SCQ) to Prague (PRG) in December 2025 (see full year).

Return flights

10 Dec - 15 Dec Vueling Airlines
01 Dec - 04 Dec Vueling Airlines
10 Dec - 14 Dec Vueling Airlines
31 Dec - 04 Jan Ryanair
11 Dec - 14 Dec Iberia
13 Dec - 15 Dec Vueling Airlines
04 Dec - 07 Dec Vueling Airlines
02 Dec - 05 Dec Vueling Airlines
08 Dec - 15 Dec Ryanair
31 Dec - 05 Jan Ryanair
06 Dec - 10 Dec Vueling Airlines
01 Dec - 05 Dec Vueling Airlines
21 Dec - 09 Jan Vueling Airlines
21 Dec - 07 Jan Vueling Airlines
21 Dec - 11 Jan Vueling Airlines
25 Dec - 02 Jan Vueling Airlines
30 Dec - 04 Jan Iberia
18 Dec - 07 Jan Vueling Airlines
25 Dec - 13 Jan Vueling Airlines
30 Dec - 06 Jan Iberia

Also check the deals for one-way flights from Santiago to Prague in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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