Cheapest return flights from Santo Domingo to Guayaquil in September from $437

AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Guayaquil (GYE) in September 2025 (see full year).

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.