Cheapest return flights from Santo Domingo to Panama City in September from $473

AirHint found the following cheapest return flights from Santo Domingo (SDQ) to Panama City (PTY) in September 2025 (see full year).

Return flights

27 Sep - 29 Sep Avianca
23 Sep - 28 Oct Avianca
23 Sep - 28 Sep Avianca
21 Sep - 28 Sep Frontier Airlines
22 Sep - 29 Sep Arajet
23 Sep - 28 Sep Copa direct
27 Sep - 29 Sep Copa direct
23 Sep - 28 Oct Copa direct
21 Sep - 28 Sep Copa direct
22 Sep - 29 Sep Copa direct

Also check the deals for one-way flights from Santo Domingo to Panama City in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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