AirHint found the following cheapest return flights from Santander (SDR) to Lisbon (LIS) in December 2025 (see full year).

Return flights

07 Dec - 10 Dec	Iberia
16 Dec - 24 Dec	Vueling Airlines
16 Dec - 17 Dec	Vueling Airlines
15 Dec - 24 Dec	Vueling Airlines
06 Dec - 09 Dec	Iberia
24 Dec - 07 Jan	Iberia
13 Dec - 18 Dec	Iberia
18 Dec - 24 Dec	Vueling Airlines
13 Dec - 24 Dec	Vueling Airlines
20 Dec - 23 Dec	Iberia
31 Dec - 04 Jan	Iberia
30 Dec - 06 Jan	Iberia
12 Dec - 14 Dec	Ryanair
18 Dec - 07 Jan	Vueling Airlines
30 Dec - 19 Jan	Vueling Airlines
30 Dec - 16 Jan	Vueling Airlines
20 Dec - 09 Jan	Vueling Airlines
27 Dec - 16 Jan	Vueling Airlines
30 Dec - 09 Jan	Vueling Airlines
30 Dec - 15 Jan	Vueling Airlines

Also check the deals for one-way flights from Santander to Lisbon in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santander to Lisbon in December from $157

Return flights