AirHint found the following cheapest return flights from Southend (SEN) to Santiago (SCL) in December 2025 (see full year).

Return flights

14 Dec - 21 Dec	easyJet
06 Dec - 20 Dec	easyJet
14 Dec - 31 Dec	easyJet
28 Dec - 31 Jan	easyJet
11 Dec - 29 Dec	easyJet
05 Dec - 31 Dec	easyJet
04 Dec - 29 Dec	easyJet
07 Dec - 28 Dec	easyJet
04 Dec - 17 Jan	easyJet
13 Dec - 31 Dec	easyJet
13 Dec - 07 Jan	easyJet
24 Dec - 10 Jan	easyJet
11 Dec - 01 Jan	easyJet
18 Dec - 01 Jan	easyJet
26 Dec - 07 Jan	easyJet
14 Dec - 07 Jan	easyJet
21 Dec - 10 Jan	easyJet
14 Dec - 04 Jan	easyJet

Also check the deals for one-way flights from Southend to Santiago in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Southend to Santiago in December from $1517

Return flights