AirHint found the following cheapest return flights from San Francisco (SFO) to Guangzhou (CAN) in December 2025 (see full year).

Return flights

01 Dec - 20 Dec	Air China
30 Dec - 27 Jan	Korean Air
02 Dec - 25 Dec	Cathay Pacific
04 Dec - 25 Dec	Cathay Pacific
08 Dec - 23 Dec	Cathay Pacific
04 Dec - 12 Dec	China Eastern
03 Dec - 16 Dec	Cathay Pacific
01 Dec - 08 Dec	Cathay Pacific
27 Dec - 24 Jan	Korean Air
09 Dec - 26 Dec	Cathay Pacific
29 Dec - 15 Jan	Turkish Airlines
04 Dec - 16 Dec	Cathay Pacific
09 Dec - 16 Dec	Cathay Pacific
25 Dec - 19 Jan	China Southern
29 Dec - 13 Jan	China Southern
08 Dec - 13 Jan	Japan Airlines
09 Dec - 13 Jan	Alaska Airlines
06 Dec - 13 Jan	Air China
24 Dec - 14 Jan	Air China
16 Dec - 16 Jan	Frontier Airlines

Also check the deals for one-way flights from San Francisco to Guangzhou in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Guangzhou in December from $771

Return flights