AirHint found the following cheapest return flights from San Francisco (SFO) to Guadalajara (GDL) in December 2025 (see full year).

Return flights

11 Dec - 21 Dec	Frontier Airlines
01 Dec - 14 Dec	Aeromexico
30 Dec - 06 Jan	Alaska Airlines
05 Dec - 19 Dec	Aeromexico
14 Dec - 17 Jan	Alaska Airlines
06 Dec - 15 Dec	Aeromexico
05 Dec - 20 Dec	Aeromexico
12 Dec - 21 Dec	Aeromexico	direct
02 Dec - 20 Dec	Aeromexico
13 Dec - 10 Jan	Frontier Airlines
11 Dec - 21 Dec	Aeromexico	direct
13 Dec - 21 Dec	Aeromexico	direct
25 Dec - 03 Jan	Aeromexico
30 Dec - 06 Jan	Aeromexico	direct
19 Dec - 31 Dec	Frontier Airlines
19 Dec - 18 Jan	Frontier Airlines
14 Dec - 17 Jan	Aeromexico	direct
16 Dec - 06 Jan	Aeromexico	direct
13 Dec - 10 Jan	Delta	direct
25 Dec - 05 Jan	Aeromexico

Also check the deals for one-way flights from San Francisco to Guadalajara in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Guadalajara in December from $370

Return flights