AirHint found the following cheapest return flights from San Francisco (SFO) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

06 Sep - 16 Sep	Air Canada
30 Sep - 23 Oct	Avianca
18 Sep - 28 Sep	Avianca
17 Sep - 27 Sep	Avianca
22 Sep - 02 Oct	Avianca
28 Sep - 08 Oct	Avianca
08 Sep - 22 Sep	Copa
16 Sep - 18 Sep	Copa
07 Sep - 10 Sep	Copa
08 Sep - 15 Sep	Copa
30 Sep - 10 Oct	Avianca
12 Sep - 23 Sep	jetBlue
18 Sep - 22 Sep	LATAM Airlines Group
12 Sep - 22 Sep	jetBlue
26 Sep - 05 Oct	Delta
26 Sep - 06 Oct	LATAM Airlines Group
24 Sep - 04 Oct	Avianca

Also check the deals for one-way flights from San Francisco to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Sao Paulo in September from $602

Return flights