AirHint found the following cheapest return flights from San Francisco (SFO) to Guatemala City (GUA) in September 2025 (see full year).

Return flights

15 Sep - 23 Sep	United
19 Sep - 04 Oct	United
13 Sep - 18 Sep	Alaska Airlines
12 Sep - 22 Sep	Frontier Airlines
04 Sep - 11 Sep	Frontier Airlines
08 Sep - 30 Sep	Alaska Airlines
04 Sep - 14 Sep	Frontier Airlines
13 Sep - 16 Sep	Alaska Airlines
06 Sep - 10 Sep	Alaska Airlines
07 Sep - 11 Sep	Alaska Airlines

Also check the deals for one-way flights from San Francisco to Guatemala City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Guatemala City in September from $321

Return flights