AirHint found the following cheapest return flights from San Francisco (SFO) to Islamabad (ISB) in December 2025 (see full year).

Return flights

31 Dec - 20 Jan	Turkish Airlines
30 Dec - 17 Jan	Turkish Airlines
30 Dec - 15 Jan	SWISS
28 Dec - 19 Jan	Turkish Airlines
29 Dec - 15 Jan	Air India
31 Dec - 12 Jan	Turkish Airlines
31 Dec - 14 Jan	Qatar Airways
29 Dec - 11 Jan	Qatar Airways
29 Dec - 10 Jan	Turkish Airlines
28 Dec - 12 Jan	Air India
15 Dec - 23 Dec	Lufthansa
16 Dec - 23 Dec	Turkish Airlines
16 Dec - 28 Dec	Alaska Airlines
18 Dec - 31 Dec	Air India
20 Dec - 28 Dec	Sun Country Airlines
20 Dec - 27 Dec	Sun Country Airlines

Also check the deals for one-way flights from San Francisco to Islamabad in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Islamabad in December from $1049

Return flights