Cheapest return flights from San Francisco to Istanbul in October from $586

AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in October 2025 (see full year).

Return flights

07 Oct - 21 Oct TAP
10 Oct - 24 Oct Frontier Airlines
01 Oct - 15 Oct Hawaiian Airlines
08 Oct - 15 Oct SWISS
22 Oct - 05 Nov SWISS
03 Oct - 21 Oct Hawaiian Airlines
23 Oct - 05 Nov Air France
06 Oct - 22 Oct WestJet
03 Oct - 11 Oct Hawaiian Airlines
16 Oct - 28 Oct KLM
12 Oct - 26 Oct Air France
15 Oct - 22 Oct Lufthansa
07 Oct - 19 Nov Delta
29 Oct - 24 Nov Lufthansa
22 Oct - 05 Nov Turkish Airlines direct
23 Oct - 05 Nov Turkish Airlines direct

Also check the deals for one-way flights from San Francisco to Istanbul in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Feel free to contact us with any feedback or request another flight research.