AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in December 2025 (see full year).

Return flights

06 Dec - 25 Jan	Lufthansa
06 Dec - 21 Jan	Lufthansa
05 Dec - 12 Dec	Lufthansa
02 Dec - 09 Dec	Lufthansa
06 Dec - 25 Dec	Delta
31 Dec - 24 Jan	Delta
04 Dec - 20 Jan	Delta
30 Dec - 24 Jan	Delta
01 Dec - 07 Dec	Lufthansa
11 Dec - 17 Dec	Delta
03 Dec - 13 Dec	Lufthansa
09 Dec - 23 Dec	Lufthansa
05 Dec - 20 Jan	KLM
28 Dec - 22 Jan	Air France
28 Dec - 23 Jan	Air France
28 Dec - 24 Jan	Air France
28 Dec - 20 Jan	Air France
06 Dec - 25 Dec	Turkish Airlines	direct
03 Dec - 27 Dec	Turkish Airlines	direct
11 Dec - 18 Dec	Air Canada

Also check the deals for one-way flights from San Francisco to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Istanbul in December from $519

Return flights