AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in December 2025 (see full year).

Return flights

31 Dec - 20 Jan	KLM
29 Dec - 31 Jan	Brussels Airlines
31 Dec - 20 Jan	Turkish Airlines	direct
13 Dec - 16 Dec	Lufthansa
15 Dec - 10 Jan	Aer Lingus
13 Dec - 10 Jan	Lufthansa
16 Dec - 29 Jan	WestJet
14 Dec - 20 Jan	Aer Lingus
14 Dec - 21 Dec	Aer Lingus
13 Dec - 19 Dec	Aer Lingus
14 Dec - 17 Dec	Aer Lingus
16 Dec - 25 Dec	WestJet
13 Dec - 27 Dec	Lufthansa
15 Dec - 19 Dec	Air Canada
14 Dec - 19 Dec	Aer Lingus
15 Dec - 20 Dec	Aer Lingus
14 Dec - 06 Jan	Aer Lingus
24 Dec - 31 Dec	Austrian Airlines
24 Dec - 01 Jan	Austrian Airlines
17 Dec - 10 Jan	Alaska Airlines

Also check the deals for one-way flights from San Francisco to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from San Francisco to Istanbul in December from $719

Return flights