AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in December 2025 (see full year).

Return flights

05 Dec - 28 Dec	KLM
09 Dec - 23 Dec	Air France
24 Dec - 15 Jan	Air Canada
09 Dec - 23 Dec	Turkish Airlines	direct
06 Dec - 20 Dec	Air Canada
11 Dec - 05 Jan	Air Canada
06 Dec - 20 Dec	Turkish Airlines	direct
19 Dec - 29 Dec	KLM
22 Dec - 03 Jan	Lufthansa
24 Dec - 15 Jan	Turkish Airlines	direct
19 Dec - 02 Jan	KLM
19 Dec - 05 Jan	WestJet
05 Dec - 28 Dec	Turkish Airlines	direct
21 Dec - 04 Jan	British Airways
11 Dec - 05 Jan	Turkish Airlines	direct
20 Dec - 03 Jan	Air Canada
19 Dec - 29 Dec	Turkish Airlines	direct
19 Dec - 02 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from San Francisco to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Istanbul in December from $743

Return flights