AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in December 2025 (see full year).

Return flights

09 Dec - 23 Dec	Air Canada
02 Dec - 11 Dec	Air France
06 Dec - 27 Dec	Air France
07 Dec - 27 Dec	Air France
15 Dec - 19 Jan	KLM
15 Dec - 21 Jan	KLM
15 Dec - 22 Jan	KLM
28 Dec - 14 Jan	KLM
14 Dec - 28 Dec	KLM
06 Dec - 20 Dec	Air France
16 Dec - 20 Jan	KLM
31 Dec - 06 Jan	Air France
12 Dec - 26 Dec	KLM
09 Dec - 23 Dec	Turkish Airlines	direct
02 Dec - 11 Dec	Turkish Airlines	direct
07 Dec - 05 Jan	British Airways
07 Dec - 27 Dec	Turkish Airlines	direct
28 Dec - 14 Jan	Turkish Airlines	direct
17 Dec - 22 Jan	KLM
17 Dec - 10 Jan	Frontier Airlines

Also check the deals for one-way flights from San Francisco to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Istanbul in December from $716

Return flights