AirHint found the following cheapest return flights from San Francisco (SFO) to Karachi (KHI) in December 2025 (see full year).

Return flights

31 Dec - 30 Jan	Qatar Airways
31 Dec - 15 Jan	Turkish Airlines
28 Dec - 30 Jan	Turkish Airlines
03 Dec - 09 Dec	Turkish Airlines
03 Dec - 24 Dec	Turkish Airlines
29 Dec - 30 Jan	Turkish Airlines
03 Dec - 23 Dec	Turkish Airlines
29 Dec - 31 Jan	Turkish Airlines
08 Dec - 16 Dec	Turkish Airlines
05 Dec - 12 Dec	Turkish Airlines
05 Dec - 26 Dec	Turkish Airlines
06 Dec - 11 Jan	Turkish Airlines
05 Dec - 27 Dec	Turkish Airlines
08 Dec - 08 Jan	Turkish Airlines
05 Dec - 28 Dec	Qatar Airways
26 Dec - 25 Jan	Qatar Airways
26 Dec - 11 Jan	Turkish Airlines
15 Dec - 22 Dec	Brussels Airlines
12 Dec - 26 Dec	Philippine Airlines
22 Dec - 22 Jan	Frontier Airlines

Also check the deals for one-way flights from San Francisco to Karachi in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Karachi in December from $1004

Return flights