Cheapest return flights from San Francisco to Rio Negro in October from $419

AirHint found the following cheapest return flights from San Francisco (SFO) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

14 Oct - 29 Oct jetBlue
23 Oct - 26 Oct Frontier Airlines
17 Oct - 25 Oct Frontier Airlines
17 Oct - 24 Oct Frontier Airlines
08 Oct - 13 Oct Avianca
04 Oct - 13 Oct Avianca
15 Oct - 21 Oct Copa
15 Oct - 20 Oct Copa
03 Oct - 05 Oct Avianca
14 Oct - 20 Oct Copa

Also check the deals for one-way flights from San Francisco to Rio Negro in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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