Cheapest return flights from San Francisco to Rio Negro in December from $500

AirHint found the following cheapest return flights from San Francisco (SFO) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

10 Dec - 23 Dec United
25 Dec - 13 Jan Copa
06 Dec - 03 Jan Avianca
17 Dec - 02 Jan Frontier Airlines
23 Dec - 28 Dec Alaska Airlines
24 Dec - 03 Jan jetBlue
25 Dec - 06 Jan Alaska Airlines
22 Dec - 16 Jan Copa
21 Dec - 16 Jan Alaska Airlines
21 Dec - 15 Jan Alaska Airlines

Also check the deals for one-way flights from San Francisco to Rio Negro in December.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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