Cheapest return flights from San Francisco to Prague in September from $480

AirHint found the following cheapest return flights from San Francisco (SFO) to Prague (PRG) in September 2025 (see full year).

Return flights

24 Sep - 08 Oct Condor
09 Sep - 16 Sep SWISS
16 Sep - 23 Sep SWISS
24 Sep - 01 Oct SWISS
30 Sep - 07 Oct SWISS
09 Sep - 04 Oct Air Canada
14 Sep - 21 Sep SWISS
24 Sep - 18 Oct SWISS
29 Sep - 06 Oct SWISS
15 Sep - 22 Sep SWISS
23 Sep - 28 Sep Turkish Airlines
11 Sep - 04 Oct Hawaiian Airlines
10 Sep - 13 Sep Condor
13 Sep - 20 Sep SWISS
11 Sep - 18 Sep SWISS
11 Sep - 14 Sep Condor
12 Sep - 19 Sep Lufthansa
17 Sep - 11 Oct Condor
25 Sep - 11 Oct Frontier Airlines
27 Sep - 04 Oct SWISS

Also check the deals for one-way flights from San Francisco to Prague in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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