Cheapest return flights from San Francisco to Panama City in May from $485

Best time to book flights for San Francisco (SFO) to Panama City (PTY) flights at AirHint

AirHint found the following cheapest return flights from San Francisco (SFO) to Panama City (PTY) in May 2025 (see full year).

Return flights

02 May - 05 May Avianca
05 May - 12 May Avianca
09 May - 13 May Avianca
09 May - 14 May Avianca
16 May - 21 May Avianca
23 May - 01 Jun Avianca
23 May - 01 Jun United direct
01 May - 03 May Avianca
16 May - 21 May Copa direct
09 May - 13 May Copa direct
09 May - 14 May Copa direct
02 May - 05 May Copa direct

Also check the deals for one-way flights from San Francisco to Panama City in May.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Panama City

Cheap car rent in Panama City