AirHint found the following cheapest return flights from San Jose (SJO) to Santiago (SCL) in October 2025 (see full year).

Return flights

17 Oct - 26 Oct	Avianca
01 Oct - 13 Oct	Avianca
10 Oct - 12 Oct	Avianca
02 Oct - 06 Oct	Avianca
16 Oct - 24 Oct	Avianca
01 Oct - 10 Oct	Copa
18 Oct - 24 Oct	Copa
03 Oct - 12 Oct	Copa
11 Oct - 18 Oct	Copa
16 Oct - 30 Oct	Copa
30 Oct - 03 Nov	Copa
30 Oct - 07 Nov	Copa
30 Oct - 02 Nov	Copa
27 Oct - 03 Nov	Copa

Also check the deals for one-way flights from San Jose to Santiago in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Santiago

Cheap car rent in Santiago

Cheapest return flights from San Jose to Santiago in October from $369

Return flights