AirHint found the following cheapest return flights from San Juan (SJU) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

22 Sep - 30 Sep	Copa
25 Sep - 30 Sep	Copa
22 Sep - 30 Sep	jetBlue	direct
22 Sep - 26 Sep	jetBlue	direct
20 Sep - 27 Sep	jetBlue	direct
28 Sep - 02 Oct	jetBlue	direct
26 Sep - 08 Oct	jetBlue	direct
25 Sep - 29 Sep	Copa
25 Sep - 07 Oct	Copa
18 Sep - 22 Sep	Copa
17 Sep - 23 Sep	Copa
25 Sep - 07 Oct	jetBlue	direct
26 Sep - 28 Sep	Copa
19 Sep - 21 Sep	jetBlue	direct

Also check the deals for one-way flights from San Juan to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Juan to Rio Negro in September from $224

Return flights