AirHint found the following cheapest return flights from Santa Ana (SNA) to Guatemala City (GUA) in October 2025 (see full year).

Return flights

02 Oct - 16 Oct	United
15 Oct - 29 Oct	United
16 Oct - 30 Oct	United
06 Oct - 20 Oct	United
07 Oct - 21 Oct	United
08 Oct - 22 Oct	United
09 Oct - 23 Oct	United
14 Oct - 28 Oct	United
28 Oct - 11 Nov	United
29 Oct - 12 Nov	United
22 Oct - 05 Nov	United
23 Oct - 06 Nov	United
03 Oct - 17 Oct	United
05 Oct - 19 Oct	United
18 Oct - 01 Nov	United
26 Oct - 09 Nov	United
27 Oct - 10 Nov	United
20 Oct - 03 Nov	United
21 Oct - 04 Nov	United
25 Oct - 08 Nov	United

Also check the deals for one-way flights from Santa Ana to Guatemala City in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santa Ana to Guatemala City in October from $586

Return flights