AirHint found the following cheapest return flights from Santa Ana (SNA) to Istanbul (IST) in October 2025 (see full year).

Return flights

01 Oct - 08 Oct	Spirit Airlines
07 Oct - 21 Oct	Royal Jordanian
12 Oct - 21 Oct	Royal Jordanian
01 Oct - 10 Oct	Royal Jordanian
18 Oct - 26 Oct	Royal Jordanian
11 Oct - 21 Oct	Royal Jordanian
15 Oct - 08 Nov	Royal Jordanian
20 Oct - 15 Nov	Royal Jordanian
18 Oct - 08 Nov	Royal Jordanian
17 Oct - 24 Oct	Royal Jordanian
10 Oct - 24 Oct	Royal Jordanian
19 Oct - 08 Nov	Royal Jordanian
05 Oct - 25 Oct	Royal Jordanian
03 Oct - 25 Oct	Royal Jordanian
16 Oct - 08 Nov	Royal Jordanian

Also check the deals for one-way flights from Santa Ana to Istanbul in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Istanbul

Cheap car rent in Istanbul

Cheapest return flights from Santa Ana to Istanbul in October from $741

Return flights