AirHint found the following cheapest return flights from Santa Ana (SNA) to Istanbul (IST) in December 2025 (see full year).

Return flights

25 Dec - 17 Jan	Alaska Airlines
23 Dec - 16 Jan	Alaska Airlines
24 Dec - 17 Jan	Alaska Airlines
25 Dec - 08 Jan	Alaska Airlines
25 Dec - 07 Jan	Alaska Airlines
23 Dec - 07 Jan	Alaska Airlines
13 Dec - 13 Jan	Alaska Airlines
13 Dec - 06 Jan	Royal Jordanian
14 Dec - 06 Jan	Royal Jordanian
15 Dec - 06 Jan	Royal Jordanian
23 Dec - 31 Dec	Qatar Airways
16 Dec - 30 Dec	Qatar Airways
19 Dec - 28 Dec	Qatar Airways

Also check the deals for one-way flights from Santa Ana to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santa Ana to Istanbul in December from $1189

Return flights