Cheapest return flights from Southampton to Prague in October from $220

AirHint found the following cheapest return flights from Southampton (SOU) to Prague (PRG) in October 2025 (see full year).

Return flights

06 Oct - 13 Oct easyJet
13 Oct - 15 Oct Aer Lingus
02 Oct - 06 Oct easyJet
19 Oct - 30 Oct Aer Lingus
18 Oct - 20 Oct KLM
23 Oct - 26 Oct KLM
17 Oct - 19 Oct KLM
17 Oct - 24 Oct KLM
05 Oct - 19 Oct KLM

Also check the deals for one-way flights from Southampton to Prague in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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