AirHint found the following cheapest return flights from Southampton (SOU) to Prague (PRG) in December 2025 (see full year).
Return flights
| 15 Dec - 18 Dec | easyJet | ||
| 15 Dec - 17 Dec | easyJet | ||
| 16 Dec - 18 Dec | Aer Lingus | ||
| 24 Dec - 30 Dec | Loganair | ||
| 01 Dec - 08 Dec | easyJet | ||
| 30 Dec - 02 Jan | Loganair | ||
| 22 Dec - 23 Dec | easyJet | ||
| 01 Dec - 03 Dec | Aer Lingus |
Also check the deals for one-way flights from Southampton to Prague in December.
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