AirHint found the following cheapest return flights from Southampton (SOU) to Prague (PRG) in September 2025 (see full year).
Return flights
| 24 Sep - 25 Sep | Aer Lingus | ||
| 28 Sep - 30 Sep | Aer Lingus | ||
| 20 Sep - 23 Sep | Aer Lingus | ||
| 27 Sep - 03 Oct | easyJet | ||
| 08 Sep - 10 Sep | easyJet | ||
| 10 Sep - 17 Sep | Aer Lingus | ||
| 13 Sep - 20 Sep | easyJet | ||
| 09 Sep - 16 Sep | KLM |
Also check the deals for one-way flights from Southampton to Prague in September.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
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