AirHint found the following cheapest return flights from St. Louis (STL) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 26 Dec - 15 Jan | American Airlines | ||
| 25 Dec - 15 Jan | American Airlines | ||
| 21 Dec - 28 Dec | Delta | ||
| 29 Dec - 02 Jan | Delta | ||
| 26 Dec - 02 Jan | American Airlines |
Also check the deals for one-way flights from St. Louis to Panama City in December.
The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.
Find us on social media