AirHint found the following cheapest return flights from London (STN) to Santiago (SCL) in September 2025 (see full year).

Return flights

27 Sep - 18 Oct	easyJet
27 Sep - 03 Oct	easyJet
18 Sep - 21 Oct	Jet2
29 Sep - 03 Oct	Ryanair
30 Sep - 10 Oct	Ryanair
18 Sep - 02 Oct	Ryanair
22 Sep - 10 Oct	Ryanair
24 Sep - 01 Oct	Ryanair
26 Sep - 11 Oct	Ryanair
20 Sep - 30 Sep	Ryanair
21 Sep - 28 Sep	Ryanair
24 Sep - 03 Oct	Ryanair
20 Sep - 27 Sep	Ryanair
24 Sep - 28 Sep	Ryanair
18 Sep - 26 Sep	Ryanair
19 Sep - 28 Sep	Ryanair
19 Sep - 29 Sep	Jet2
22 Sep - 28 Sep	Ryanair
21 Sep - 22 Sep	Ryanair

Also check the deals for one-way flights from London to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from London to Santiago in September from $1283

Return flights