AirHint found the following cheapest return flights from Tenerife (TFS) to Prague (PRG) in September 2025 (see full year).

Return flights

23 Sep - 29 Sep	Ryanair
22 Sep - 29 Sep	Volotea
22 Sep - 28 Sep	Volotea
27 Sep - 05 Oct	Wizz Air Malta
06 Sep - 15 Sep	easyJet
08 Sep - 12 Sep	Volotea
06 Sep - 14 Sep	British Airways
28 Sep - 06 Oct	Jet2
07 Sep - 15 Sep	Jet2
07 Sep - 12 Sep	Jet2
01 Sep - 07 Sep	KLM
22 Sep - 29 Sep	Smart Wings	direct
28 Sep - 06 Oct	Smart Wings	direct

Also check the deals for one-way flights from Tenerife to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Prague

Cheap car rent in Prague

Cheapest return flights from Tenerife to Prague in September from $199

Return flights