AirHint found the following cheapest return flights from Tampa (TPA) to Prague (PRG) in December 2025 (see full year).

Return flights

08 Dec - 24 Dec	British Airways
15 Dec - 06 Jan	Spirit Airlines
12 Dec - 20 Dec	SWISS
22 Dec - 17 Jan	Spirit Airlines
16 Dec - 06 Jan	Frontier Airlines
20 Dec - 16 Jan	Frontier Airlines
20 Dec - 17 Jan	Frontier Airlines
20 Dec - 18 Jan	Frontier Airlines
23 Dec - 04 Jan	Frontier Airlines
21 Dec - 28 Dec	British Airways
21 Dec - 04 Jan	British Airways
19 Dec - 04 Jan	Delta
27 Dec - 03 Jan	Delta

Also check the deals for one-way flights from Tampa to Prague in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Tampa to Prague in December from $492

Return flights