AirHint found the following cheapest return flights from Tampa (TPA) to Santiago (SCL) in December 2025 (see full year).
Return flights
| 28 Dec - 04 Jan | Copa | ||
| 21 Dec - 31 Dec | Avianca | ||
| 20 Dec - 27 Dec | LATAM Airlines Group | ||
| 20 Dec - 01 Jan | Avianca | ||
| 21 Dec - 02 Jan | Frontier Airlines |
Also check the deals for one-way flights from Tampa to Santiago in December.
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