AirHint found the following cheapest return flights from Trujillo (TRU) to Santiago (SCL) in September 2025 (see full year).

Return flights

17 Sep - 23 Sep	Sky Airline
16 Sep - 22 Sep	LATAM Airlines Group
17 Sep - 22 Sep	LATAM Airlines Group
22 Sep - 03 Oct	Sky Airline
13 Sep - 03 Oct	JetSmart	direct
13 Sep - 04 Oct	JetSmart	direct
13 Sep - 27 Sep	JetSmart	direct
21 Sep - 27 Sep	Sky Airline
22 Sep - 03 Oct	JetSmart	direct
22 Sep - 04 Oct	JetSmart	direct
22 Sep - 27 Sep	JetSmart	direct
21 Sep - 03 Oct	JetSmart	direct
21 Sep - 04 Oct	JetSmart	direct
21 Sep - 27 Sep	JetSmart	direct

Also check the deals for one-way flights from Trujillo to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Trujillo to Santiago in September from $230

Return flights