Cheapest return flights from Knoxville to Chicago in November from $209

AirHint found the following cheapest return flights from Knoxville (TYS) to Chicago (MDW) in November 2025 (see full year).

Return flights

03 Nov - 06 Nov Allegiant Air
25 Nov - 30 Nov Delta

Also check the deals for one-way flights from Knoxville to Chicago in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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