AirHint found the following cheapest return flights from Knoxville (TYS) to Chicago (MDW) in July 2025 (see full year).

Return flights

28 Jul - 01 Aug	Allegiant Air	direct
21 Jul - 08 Aug	Allegiant Air	direct
21 Jul - 01 Aug	Allegiant Air	direct
14 Jul - 01 Aug	Allegiant Air	direct
14 Jul - 25 Jul	Allegiant Air	direct
18 Jul - 21 Jul	Allegiant Air	direct
28 Jul - 30 Jul	Allegiant Air
25 Jul - 29 Jul	Delta
31 Jul - 02 Aug	Delta
17 Jul - 23 Jul	Delta
28 Jul - 29 Jul	Delta
13 Jul - 13 Jul	Delta

Also check the deals for one-way flights from Knoxville to Chicago in July.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Knoxville to Chicago in July from $54

Return flights