Cheapest return flights from Knoxville to Chicago in September from $88

AirHint found the following cheapest return flights from Knoxville (TYS) to Chicago (MDW) in September 2025 (see full year).

Return flights

15 Sep - 26 Sep Allegiant Air direct
15 Sep - 29 Sep Allegiant Air direct
19 Sep - 26 Sep Allegiant Air direct
19 Sep - 29 Sep Allegiant Air direct
08 Sep - 26 Sep Allegiant Air direct
08 Sep - 29 Sep Allegiant Air direct
01 Sep - 08 Sep Allegiant Air direct
19 Sep - 10 Oct Allegiant Air direct
29 Sep - 10 Oct Allegiant Air direct

Also check the deals for one-way flights from Knoxville to Chicago in September.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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