AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in October 2025 (see full year).

Return flights

16 Oct - 23 Oct	Iberia	direct
29 Oct - 08 Nov	Iberia
20 Oct - 21 Nov	Iberia
23 Oct - 23 Nov	Iberia	direct
02 Oct - 22 Oct	LATAM Airlines Group
14 Oct - 31 Oct	Avianca
13 Oct - 27 Oct	Avianca
08 Oct - 31 Oct	Avianca
08 Oct - 19 Oct	Avianca
28 Oct - 31 Oct	Avianca
09 Oct - 23 Oct	Air Europa	direct
13 Oct - 20 Oct	Avianca
20 Oct - 05 Nov	Avianca
08 Oct - 23 Oct	Avianca
17 Oct - 04 Nov	Avianca
27 Oct - 08 Nov	Iberia
09 Oct - 04 Nov	Avianca
29 Oct - 09 Nov	Avianca
26 Oct - 02 Nov	Avianca
29 Oct - 05 Nov	Iberia

Also check the deals for one-way flights from Quito to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in October from $815

Return flights