AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).

Return flights

15 Dec - 15 Jan	Iberia	direct
22 Dec - 01 Jan	Iberia	direct
22 Dec - 06 Jan	Iberia	direct
15 Dec - 06 Jan	Iberia	direct
07 Dec - 02 Jan	LATAM Airlines Group
18 Dec - 02 Jan	Iberia
21 Dec - 04 Jan	Iberia
20 Dec - 04 Jan	Iberia
19 Dec - 30 Jan	Iberia	direct
19 Dec - 03 Jan	Iberia
21 Dec - 28 Dec	Iberia	direct
09 Dec - 22 Dec	LATAM Airlines Group

Also check the deals for one-way flights from Quito to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in December from $878

Return flights