AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in December 2025 (see full year).

Return flights

09 Dec - 31 Dec	Iberia
16 Dec - 05 Jan	Iberia	direct
24 Dec - 02 Jan	LATAM Airlines Group	direct
09 Dec - 31 Dec	Iberia	direct
05 Dec - 03 Jan	Iberia	direct
24 Dec - 31 Dec	KLM
10 Dec - 27 Dec	Iberia
25 Dec - 04 Jan	LATAM Airlines Group	direct
15 Dec - 06 Jan	LATAM Airlines Group	direct
20 Dec - 10 Jan	Air Europa	direct
17 Dec - 31 Dec	Iberia
12 Dec - 07 Jan	Iberia
22 Dec - 03 Jan	Iberia
31 Dec - 07 Jan	Iberia
05 Dec - 02 Jan	Iberia
24 Dec - 31 Dec	LATAM Airlines Group	direct
10 Dec - 25 Dec	Iberia
13 Dec - 28 Dec	Iberia
20 Dec - 30 Dec	Iberia
01 Dec - 14 Dec	Avianca

Also check the deals for one-way flights from Quito to Madrid in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in December from $762

Return flights