AirHint found the following cheapest return flights from Quito (UIO) to Santiago (SCL) in November 2025 (see full year).

Return flights

12 Nov - 19 Nov	JetSmart
12 Nov - 26 Nov	JetSmart
19 Nov - 26 Nov	JetSmart
07 Nov - 19 Nov	JetSmart
07 Nov - 26 Nov	JetSmart
18 Nov - 20 Nov	Avianca
20 Nov - 23 Nov	Avianca
01 Nov - 04 Nov	LATAM Airlines Group

Also check the deals for one-way flights from Quito to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Santiago in November from $374

Return flights