AirHint found the following cheapest return flights from Quito (UIO) to Santiago (SCL) in August 2025 (see full year).

Return flights

15 Aug - 17 Aug	JetSmart
29 Aug - 03 Sep	JetSmart
15 Aug - 03 Sep	JetSmart
29 Aug - 05 Sep	JetSmart
15 Aug - 22 Aug	JetSmart
15 Aug - 24 Aug	JetSmart
31 Aug - 03 Sep	JetSmart
15 Aug - 05 Sep	JetSmart
11 Aug - 22 Aug	JetSmart
10 Aug - 22 Aug	JetSmart
31 Aug - 21 Sep	JetSmart
11 Aug - 24 Aug	JetSmart
10 Aug - 24 Aug	JetSmart
31 Aug - 05 Sep	JetSmart
10 Aug - 17 Aug	JetSmart
15 Aug - 29 Aug	JetSmart
01 Aug - 03 Aug	JetSmart
20 Aug - 03 Sep	JetSmart
20 Aug - 05 Sep	JetSmart
01 Aug - 01 Sep	JetSmart

Also check the deals for one-way flights from Quito to Santiago in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Santiago in August from $340

Return flights