Cheapest return flights from Quito to Santiago in September from $378

Best time to book flights for Quito (UIO) to Santiago (SCL) flights at AirHint

AirHint found the following cheapest return flights from Quito (UIO) to Santiago (SCL) in September 2025 (see full year).

Return flights

24 Sep - 28 Sep JetSmart
26 Sep - 28 Sep JetSmart
17 Sep - 28 Sep JetSmart
07 Sep - 28 Sep JetSmart
26 Sep - 18 Oct JetSmart
24 Sep - 01 Oct JetSmart
26 Sep - 01 Oct JetSmart
17 Sep - 01 Oct JetSmart
19 Sep - 28 Sep JetSmart
18 Sep - 25 Sep Avianca
19 Sep - 01 Oct JetSmart
19 Sep - 29 Sep Avianca
10 Sep - 23 Sep Copa
09 Sep - 24 Sep Copa
25 Sep - 20 Oct LATAM Airlines Group
01 Sep - 08 Sep LATAM Airlines Group

Also check the deals for one-way flights from Quito to Santiago in September.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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