Cheapest one-way flights from Cartagena to Madrid in October from $423

Best time to book flights for Cartagena (CTG) to Madrid (MAD) flights at AirHint

AirHint found the following cheapest one-way flights from Cartagena (CTG) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

04 Oct Spirit Airlines
16 Oct Plus Ultra Lineas Aereas direct
08 Oct Plus Ultra Lineas Aereas direct
07 Oct Spirit Airlines
05 Oct Spirit Airlines
02 Oct Spirit Airlines
19 Oct KLM
29 Oct KLM
15 Oct KLM
12 Oct KLM

Also check the deals for return flights from Cartagena to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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